Cargando…

miR-137 targets the inhibition of TCF4 to reverse the progression of osteoarthritis through the AMPK/NF-κB signaling pathway

Purpose: To explore the regulatory mechanism of miR-137 and transcription factor 4 (TCF4) in the progression of osteoarthritis (OA). Patients and Methods: The expressions of miR-137 and TCF4 were detected in OA cartilage tissue, chondrocytes and OA rat cartilage tissue. miR-137 and TCF4 were up-regu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jinyu, Fang, Liming, Ye, Lili, Ma, Shiliang, Huang, Haoran, Lan, Xiaoquan, Ma, Jianlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295621/ https://www.ncbi.nlm.nih.gov/pubmed/32432314 http://dx.doi.org/10.1042/BSR20200466

Ejemplares similares

A miR-19 regulon that controls NF-κB signaling
por: Gantier, Michael P., et al.
Publicado: (2012)

DNA mimicry by a high-affinity anti-NF-κB RNA aptamer
por: Reiter, Nicholas J., et al.
Publicado: (2008)

Characterization of anti-NF-κB RNA aptamer-binding specificity in vitro and in the yeast three-hybrid system
por: Wurster, Susan E., et al.
Publicado: (2009)

NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells
por: Galardi, Silvia, et al.
Publicado: (2011)

CCAL1 enhances osteoarthritis through the NF‐κB/AMPK signaling pathway
por: Zhu, Hanzhong, et al.
Publicado: (2020)

The G-patch protein NF-κB-repressing factor mediates the recruitment of the exonuclease XRN2 and activation of the RNA helicase DHX15 in human ribosome biogenesis
por: Memet, Indira, et al.
Publicado: (2017)

Cooperative translational control of polymorphic BAFF by NF90 and miR-15a
por: Idda, M Laura, et al.
Publicado: (2018)

Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
por: Li, Ningning, et al.
Publicado: (2013)

Transcriptome-wide stability analysis uncovers LARP4-mediated NFκB1 mRNA stabilization during T cell activation
por: Tian, Yi, et al.
Publicado: (2020)

Differential activation and functional specialization of miR-146 and miR-155 in innate immune sensing
por: Schulte, Leon N., et al.
Publicado: (2013)

The Long Noncoding RNA LINC00963 Inhibits Corneal Fibrosis Scar Formation by Targeting miR-143-3p
por: Zhang, Lixia, et al.
Publicado: (2022)

CircTHBS1 targeting miR-211/CCND2 pathway to promote cell proliferation and migration potential in primary cystitis glandularis cells
por: Ma, Yue, et al.
Publicado: (2021)

Aptamers that recognize drug-resistant HIV-1 reverse transcriptase
por: Li, Na, et al.
Publicado: (2008)

No effect of schizophrenia risk genes MIR137, TCF4, and ZNF804A on macroscopic brain structure
por: Cousijn, Helena, et al.
Publicado: (2014)

Human miR-1271 is a miR-96 paralog with distinct non-conserved brain expression pattern
por: Jensen, Kevin P., et al.
Publicado: (2011)

Molecular basis of differential target regulation by miR-96 and miR-182: the Glypican-3 as a model
por: Jalvy-Delvaille, Sandra, et al.
Publicado: (2012)

NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif
por: Kuwano, Yuki, et al.
Publicado: (2010)

LncRNA PCAT1 activates AKT and NF-κB signaling in castration-resistant prostate cancer by regulating the PHLPP/FKBP51/IKKα complex
por: Shang, Zhiqun, et al.
Publicado: (2019)

Virion packaging determinants and reverse transcription of SRP RNA in HIV-1 particles
por: Tian, Chunjuan, et al.
Publicado: (2007)

The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent
por: Hauenschild, Ralf, et al.
Publicado: (2015)

Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells
por: Wickramasinghe, Nalinie S., et al.
Publicado: (2009)

The availability of the primer activation signal (PAS) affects the efficiency of HIV-1 reverse transcription initiation
por: Ooms, Marcel, et al.
Publicado: (2007)

The RNA ligase RtcB reverses MazF-induced ribosome heterogeneity in Escherichia coli
por: Temmel, Hannes, et al.
Publicado: (2017)

Mechanical stress protects against osteoarthritis via regulation of the AMPK/NF‐κB signaling pathway
por: Yang, Yue, et al.
Publicado: (2018)

EBP1 and DRBP76/NF90 binding proteins are included in the major histocompatibility complex class II RNA operon
por: Corso, Carmela, et al.
Publicado: (2011)

RBM3 regulates temperature sensitive miR-142–5p and miR-143 (thermomiRs), which target immune genes and control fever
por: Wong, Justin J.-L., et al.
Publicado: (2016)

miR-152 Attenuates Apoptosis in Chondrocytes and Degeneration of Cartilages in Osteoarthritis Rats via TCF-4 Pathway
por: Wan, Daqian, et al.
Publicado: (2020)

Evolution of Arabidopsis MIR genes generates novel microRNA classes
por: Vazquez, Franck, et al.
Publicado: (2008)

Regulation of somatic cell reprogramming through inducible mir-302 expression
por: Lin, Shi-Lung, et al.
Publicado: (2011)

Miravirsen (SPC3649) can inhibit the biogenesis of miR-122
por: Gebert, Luca F. R., et al.
Publicado: (2014)

Trans-lesion synthesis and RNaseH activity by reverse transcriptases on a true abasic RNA template
por: Küpfer, Pascal A., et al.
Publicado: (2007)

MicroRNA miR-92a-1 biogenesis and mRNA targeting is modulated by a tertiary contact within the miR-17∼92 microRNA cluster
por: Chaulk, Steven G., et al.
Publicado: (2014)

Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase
por: Nguyen, Phuong D M, et al.
Publicado: (2020)

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids
por: Fabani, Martin M., et al.
Publicado: (2010)

Post-transcriptional modification mapping in the Clostridium acetobutylicum 16S rRNA by mass spectrometry and reverse transcriptase assays
por: Emmerechts, Gert, et al.
Publicado: (2007)

Human telomerase reverse transcriptase binds to a pre-organized hTR in vivo exposing its template
por: Zemora, Georgeta, et al.
Publicado: (2016)

RNA–protein interactions govern antiviral specificity and encapsidation of broad spectrum anti-HIV reverse transcriptase aptamers
por: Lange, Margaret J., et al.
Publicado: (2017)

Vif is a RNA chaperone that could temporally regulate RNA dimerization and the early steps of HIV-1 reverse transcription
por: Henriet, S., et al.
Publicado: (2007)

High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase
por: Ditzler, Mark A., et al.
Publicado: (2013)

The structural stabilization of the κ three-way junction by Mg(II) represents the first step in the folding of a group II intron
por: Donghi, Daniela, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_j0k9qe7sjrnl4qi0vlo0qdj32p