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MicroRNA-27a targets Sfrp1 to induce renal fibrosis in diabetic nephropathy by activating Wnt/β-Catenin signalling

Diabetic nephropathy (DN) commonly causes end-stage renal disease (ESRD). Increasing evidence indicates that abnormal miRNA expression is tightly associated with chronic kidney disease (CKD). This work aimed to investigate whether miR-27a can promote the occurrence of renal fibrosis in DN by suppres...

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Detalles Bibliográficos
Autores principales: Shi, MingJun, Tian, PingPing, Liu, ZhongQiang, Zhang, Fan, Zhang, YingYing, Qu, LingLing, Liu, XingMei, Wang, YuanYuan, Zhou, XingCheng, Xiao, Ying, Guo, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295625/
https://www.ncbi.nlm.nih.gov/pubmed/32484208
http://dx.doi.org/10.1042/BSR20192794