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Up-regulation of miR-34c-5p inhibits nasopharyngeal carcinoma cells by mediating NOTCH1

Objective: To explore the correlation between miR-34c-5p and NOTCH1 in nasopharyngeal carcinoma (NPC). Materials and methods: qPCR was employed to quantify miR-34c-5p and NOTCH1 mRNA in NPC, and Western blot to detect NOTCH1. MiR-34c-5p mimics/inhibitor and NOTCH1 siRNA were constructed to analyze t...

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Detalles Bibliográficos
Autores principales: Xu, Xin, Yan, Haomin, Zhang, Le, Liu, Jing, Huang, Yu, Cheng, Haoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295627/
https://www.ncbi.nlm.nih.gov/pubmed/32458967
http://dx.doi.org/10.1042/BSR20200302