Physiological cyclic stretch up-regulates angiotensin-converting enzyme 2 expression to reduce proliferation and migration of vascular smooth muscle cells

Angiotensin-converting enzyme 2 (ACE2) is considered as an endogenous negative regulator of renin–angiotensin system (RAS), exerting multiple cardiovascular protective roles. Whether mechanical stretch modulates ACE2 expression remains unknown. The present study aimed at investigating whether ACE2 i...

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Detalles Bibliográficos
Autores principales: Song, Jiantao, Qu, Haiyan, Hu, Bo, Bi, Chenglong, Li, Mengmeng, Wang, Lin, Huang, Xiaozhen, Zhang, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cardiovascular System & Vascular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295630/
https://www.ncbi.nlm.nih.gov/pubmed/32463098
http://dx.doi.org/10.1042/BSR20192012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295630/
https://www.ncbi.nlm.nih.gov/pubmed/32463098
http://dx.doi.org/10.1042/BSR20192012

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