Cargando…

Physiological cyclic stretch up-regulates angiotensin-converting enzyme 2 expression to reduce proliferation and migration of vascular smooth muscle cells

Angiotensin-converting enzyme 2 (ACE2) is considered as an endogenous negative regulator of renin–angiotensin system (RAS), exerting multiple cardiovascular protective roles. Whether mechanical stretch modulates ACE2 expression remains unknown. The present study aimed at investigating whether ACE2 i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Jiantao, Qu, Haiyan, Hu, Bo, Bi, Chenglong, Li, Mengmeng, Wang, Lin, Huang, Xiaozhen, Zhang, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Cardiovascular System & Vascular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295630/ https://www.ncbi.nlm.nih.gov/pubmed/32463098 http://dx.doi.org/10.1042/BSR20192012

Ejemplares similares

Angiotensin-converting enzyme 2 and COVID-19 in cardiorenal diseases
por: Sharma, Ravindra K., et al.
Publicado: (2021)

Effect of rs4646994 polymorphism of angiotensin-converting enzyme on the risk of nonischemic cardiomyopathy
por: Shen, Jinsheng, et al.
Publicado: (2021)

Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers: potential allies in the COVID-19 pandemic instead of a threat?
por: Simko, Fedor, et al.
Publicado: (2021)

The serum angiotensin-converting enzyme 2 and angiotensin-(1-7) concentrations after optimal therapy for acute decompensated heart failure with reduced ejection fraction
por: Hisatake, Shinji, et al.
Publicado: (2020)

Beneficial effects of brief early life angiotensin-converting enzyme inhibition wane with time in sheep with solitary functioning kidney
por: McArdle, Zoe, et al.
Publicado: (2023)

Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm
por: Jadli, Anshul S., et al.
Publicado: (2023)

MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2
por: Wang, Haijun, et al.
Publicado: (2020)

PKN2 deficiency leads both to prenatal ‘congenital’ cardiomyopathy and defective angiotensin II stress responses
por: Marshall, Jacqueline J.T., et al.
Publicado: (2022)

CGP42112: the full AT(2) receptor agonist and its role in the renin–angiotensin–aldosterone system: no longer misunderstood
por: Restrepo, Yazmin M., et al.
Publicado: (2022)

Uremic serum-induced calcification of human aortic smooth muscle cells is a regulated process involving Klotho and RUNX2
por: Patidar, Ashish, et al.
Publicado: (2019)

Transmural variations in gene expression of stretch-modulated proteins in the rat left ventricle
por: Stones, R., et al.
Publicado: (2007)

Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function
por: Zou, Zhi-Guo, et al.
Publicado: (2020)

Central role for BRAF in cardiac hypertrophy: rethinking the pathological–physiological divide
por: Altara, Raffaele, et al.
Publicado: (2023)

Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers: Anti-arrhythmic Drug for Arrhythmogenic Right Ventricular Cardiomyopathy
por: Tu, Bin, et al.
Publicado: (2021)

Impact of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on the Inflammatory Response and Viral Clearance in COVID-19 Patients
por: Huang, Linna, et al.
Publicado: (2021)

The controversy of using angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in COVID-19 patients
por: Harky, Amer, et al.
Publicado: (2021)

Mechanical Stretch Suppresses microRNA-145 Expression by Activating Extracellular Signal-Regulated Kinase 1/2 and Upregulating Angiotensin-Converting Enzyme to Alter Vascular Smooth Muscle Cell Phenotype
por: Hu, Bo, et al.
Publicado: (2014)

Atorvastatin improves the proliferation and migration of endothelial progenitor cells via the miR-221/VEGFA axis
por: Sun, Lihua, et al.
Publicado: (2020)

Involvement of amylin B-H(2)S-connexin 43 signaling pathway in vascular dysfunction and enhanced ischemia–reperfusion-induced myocardial injury in diabetic rats
por: Liu, Xiaoyong, et al.
Publicado: (2020)

Angiotensin Converting Enzymes
por: Wong, Marty K.S.
Publicado: (2016)

Angiotensin converting enzyme
por: Wong, Marty Kwok-Shing
Publicado: (2021)

Angiotensin-Converting Enzyme-2
por: Clarke, Nicola E., et al.
Publicado: (2013)

Angiotensin-converting enzyme activity and inhibition in dogs with cardiac disease and an angiotensin-converting enzyme polymorphism
por: Meurs, Kathryn M, et al.
Publicado: (2017)

Dietary Potassium Downregulates Angiotensin-I Converting Enzyme, Renin, and Angiotensin Converting Enzyme 2
por: Vio, Carlos P., et al.
Publicado: (2020)

Angiotensin Converting Enzyme Regulates Cell Proliferation and Migration
por: de Alvarenga, Erika Costa, et al.
Publicado: (2016)

Cyclic (68)Ga-Labeled Peptides for Specific Detection of Human Angiotensin-Converting Enzyme 2
por: Parker, Matthew F.L., et al.
Publicado: (2021)

Angiotensin-Converting Enzyme 2 and Antihypertensives (Angiotensin Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors) in Coronavirus Disease 2019
por: Sanchis-Gomar, Fabian, et al.
Publicado: (2020)

Brief early life angiotensin-converting enzyme inhibition attenuates the diuretic response to saline loading in sheep with solitary functioning kidney
por: McArdle, Zoe, et al.
Publicado: (2023)

Why Is COVID-19 More Severe in Patients With Diabetes? The Role of Angiotensin-Converting Enzyme 2, Endothelial Dysfunction and the Immunoinflammatory System
por: Roberts, Jacob, et al.
Publicado: (2021)

Vitamin D deficiency promotes large rupture-prone abdominal aortic aneurysms and cholecalciferol supplementation limits progression of aneurysms in a mouse model
por: Nsengiyumva, Vianne, et al.
Publicado: (2020)

Tim-3 promotes tube formation and decreases tight junction formation in vascular endothelial cells
por: Cong, Yizi, et al.
Publicado: (2020)

Experimental evidence and network pharmacology-based analysis reveal the molecular mechanism of Tongxinluo capsule administered in coronary heart diseases
por: Li, Guode, et al.
Publicado: (2020)

Association between ALMS 1 variants and early-onset coronary artery disease: a case–control study in Chinese population
por: Zhang, Shao-Yan, et al.
Publicado: (2020)

Neuregulins: protective and reparative growth factors in multiple forms of cardiovascular disease
por: Geissler, Andrew, et al.
Publicado: (2020)

Identification of feature autophagy-related genes in patients with acute myocardial infarction based on bioinformatics analyses
por: Du, Yajuan, et al.
Publicado: (2020)

Gene polymorphism associated with angiotensinogen (M235T), endothelial lipase (584C/T) and susceptibility to coronary artery disease: a meta-analysis
por: Zhao, Hongyan, et al.
Publicado: (2020)

MicroRNAs in ascending thoracic aortic aneurysms
por: Moushi, Areti, et al.
Publicado: (2020)

The coronary artery calcium score is linked to plasma cholesterol synthesis and absorption markers: Brazilian Longitudinal Study of Adult Health
por: Nunes, Valéria Sutti, et al.
Publicado: (2020)

miRNA-1183-targeted regulation of Bcl-2 contributes to the pathogenesis of rheumatic heart disease
por: Li, Ni, et al.
Publicado: (2020)

APLP2 gene polymorphisms are associated with high TC and LDL-C levels in Chinese population in Xinjiang, China
por: Abuzhalihan, Jialin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6hj7mh4ja3fo6mv64tskpbamuf