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CCL20 induced by visfatin in macrophages via the NF-κB and MKK3/6-p38 signaling pathways contributes to hepatic stellate cell activation

Chemokines interact with hepatic resident cells during inflammation and fibrosis. CC chemokine ligand (CCL) 20 has been reported to be important in inflammation and fibrosis in the liver. We hypothesized that visfatin, an adipocytokine, could play a role in hepatic fibrosis via CCL20. We investigate...

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Detalles Bibliográficos
Autores principales: Heo, Yu Jung, Choi, Sung-E, Lee, Nami, Jeon, Ja Young, Han, Seung Jin, Kim, Dae Jung, Kang, Yup, Lee, Kwan Woo, Kim, Hae Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295719/
https://www.ncbi.nlm.nih.gov/pubmed/32418112
http://dx.doi.org/10.1007/s11033-020-05510-7