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Mir34a constrains pancreatic carcinogenesis

Several studies have shown that over 70 different microRNAs are aberrantly expressed in pancreatic ductal adenocarcinoma (PDAC), affecting proliferation, apoptosis, metabolism, EMT and metastasis. The most important genetic alterations driving PDAC are a constitutive active mutation of the oncogene...

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Detalles Bibliográficos
Autores principales: Hidalgo-Sastre, Ana, Lubeseder-Martellato, Clara, Engleitner, Thomas, Steiger, Katja, Zhong, Suyang, Desztics, Judit, Öllinger, Rupert, Rad, Roland, Schmid, Roland M., Hermeking, Heiko, Siveke, Jens T., von Figura, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295749/
https://www.ncbi.nlm.nih.gov/pubmed/32541781
http://dx.doi.org/10.1038/s41598-020-66561-1