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Mir34a constrains pancreatic carcinogenesis
Several studies have shown that over 70 different microRNAs are aberrantly expressed in pancreatic ductal adenocarcinoma (PDAC), affecting proliferation, apoptosis, metabolism, EMT and metastasis. The most important genetic alterations driving PDAC are a constitutive active mutation of the oncogene...
Autores principales: | Hidalgo-Sastre, Ana, Lubeseder-Martellato, Clara, Engleitner, Thomas, Steiger, Katja, Zhong, Suyang, Desztics, Judit, Öllinger, Rupert, Rad, Roland, Schmid, Roland M., Hermeking, Heiko, Siveke, Jens T., von Figura, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295749/ https://www.ncbi.nlm.nih.gov/pubmed/32541781 http://dx.doi.org/10.1038/s41598-020-66561-1 |
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