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In vitro Differentiation of Human TERT-Transfected Multi-Lineage Progenitor Cells (MLPC) into Immortalized Hepatocyte-Like Cells

BACKGROUND: Research directed towards drug development, metabolism, and liver functions often utilize primary hepatocytes (PH) for preliminary in vitro studies. Variability in the in vitro functionality of PH and the unsuitability of hepatocarcinoma cells for these studies have driven researchers to...

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Detalles Bibliográficos
Autores principales: Collins, Daniel P, Hapke, Joel H, Aravalli, Rajagopal N, Steer, Clifford J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295760/
https://www.ncbi.nlm.nih.gov/pubmed/32607015
http://dx.doi.org/10.2147/HMER.S245916