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Tumor spheroids under perfusion within a 3D microfluidic platform reveal critical roles of cell-cell adhesion in tumor invasion

Tumor invasion within the interstitial space is critically regulated by the force balance between cell-extracellular matrix (ECM) and cell-cell interactions. Interstitial flows (IFs) are present in both healthy and diseased tissues. However, the roles of IFs in modulating cell force balance and subs...

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Detalles Bibliográficos
Autores principales: Huang, Yu Ling, Ma, Yujie, Wu, Cindy, Shiau, Carina, Segall, Jeffrey E., Wu, Mingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295764/
https://www.ncbi.nlm.nih.gov/pubmed/32541776
http://dx.doi.org/10.1038/s41598-020-66528-2