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Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma

The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles in promoting malignant growth of glioblastoma (GBM), the most lethal brain tumor. However, the molecular mechanisms underlying this crosstalk are incompletely understood. Here, we show that GSCs secrete...

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Detalles Bibliográficos
Autores principales: Tao, Weiwei, Chu, Chengwei, Zhou, Wenchao, Huang, Zhi, Zhai, Kui, Fang, Xiaoguang, Huang, Qian, Zhang, Aili, Wang, Xiuxing, Yu, Xingjiang, Huang, Haidong, Wu, Qiulian, Sloan, Andrew E., Yu, Jennifer S., Li, Xiaoxia, Stark, George R., Rich, Jeremy N., Bao, Shideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295765/
https://www.ncbi.nlm.nih.gov/pubmed/32541784
http://dx.doi.org/10.1038/s41467-020-16827-z