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Convergence of therapy-induced senescence (TIS) and EMT in multistep carcinogenesis: current opinions and emerging perspectives

Drug induced resistance is a widespread problem in the clinical management of cancer. Cancer cells, when exposed to cytotoxic drugs, can reprogram their cellular machinery and resist cell death. Evasion of cell death mechanisms, such as apoptosis and necroptosis, are part of a transcriptional reprog...

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Detalles Bibliográficos
Autores principales: Faheem, Mir Mohd, Seligson, Nathan D., Ahmad, Syed Mudabir, Rasool, Reyaz Ur, Gandhi, Sumit G., Bhagat, Madhulika, Goswami, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295779/
https://www.ncbi.nlm.nih.gov/pubmed/32566256
http://dx.doi.org/10.1038/s41420-020-0286-z