Human cytomegalovirus pp65 peptide-induced autoantibodies cross-reacts with TAF9 protein and induces lupus-like autoimmunity in BALB/c mice

Human cytomegalovirus (HCMV) has been linked to the triggering of systemic lupus erythematosus (SLE). We proposed that B cell epitope region of HCMV phosphoprotein 65 (HCMVpp65)(422–439) mimics an endogenous antigen and initiates lupus-like autoimmunity. Amino acid homology between HCMVpp65(422-439)...

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Detalles Bibliográficos
Autores principales: Hsieh, Ao-Ho, Kuo, Chang-Fu, Chou, I-Jun, Tseng, Wen-Yi, Chen, Yen-Fu, Yu, Kuang-Hui, Luo, Shue-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295797/
https://www.ncbi.nlm.nih.gov/pubmed/32541894
http://dx.doi.org/10.1038/s41598-020-66804-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295797/
https://www.ncbi.nlm.nih.gov/pubmed/32541894
http://dx.doi.org/10.1038/s41598-020-66804-1

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