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microRNA-181c-5p promotes the formation of insulin-producing cells from human induced pluripotent stem cells by targeting smad7 and TGIF2

Generating insulin-producing cells (IPCs) from human pluripotent stem cells is a promising method for studying the molecular mechanism underlying pancreas development and a potential treatment source for type 1 diabetes. Previous studies have shown that miR-181c-5p is highly enriched in adult islets...

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Detalles Bibliográficos
Autores principales: Li, Ning, Jiang, Doukou, He, Qian, He, Fei, Li, Yang, Deng, Chunyan, Li, Furong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295798/
https://www.ncbi.nlm.nih.gov/pubmed/32541687
http://dx.doi.org/10.1038/s41419-020-2668-9