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microRNA-181c-5p promotes the formation of insulin-producing cells from human induced pluripotent stem cells by targeting smad7 and TGIF2
Generating insulin-producing cells (IPCs) from human pluripotent stem cells is a promising method for studying the molecular mechanism underlying pancreas development and a potential treatment source for type 1 diabetes. Previous studies have shown that miR-181c-5p is highly enriched in adult islets...
Autores principales: | Li, Ning, Jiang, Doukou, He, Qian, He, Fei, Li, Yang, Deng, Chunyan, Li, Furong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295798/ https://www.ncbi.nlm.nih.gov/pubmed/32541687 http://dx.doi.org/10.1038/s41419-020-2668-9 |
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