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Activated α(2)-macroglobulin binding to cell surface GRP78 induces trophoblastic cell fusion

The villous cytotrophoblastic cells have the ability to fuse and differentiate, forming the syncytiotrophoblast (STB). The syncytialisation process is essential for placentation. Nevertheless, the mechanisms involved in cell fusion and differentiation are yet to be fully elucidated. It has been sugg...

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Detalles Bibliográficos
Autores principales: Bastida-Ruiz, Daniel, Wuillemin, Christine, Pederencino, Aude, Yaron, Michal, Martinez de Tejada, Begoña, Pizzo, Salvatore Vincent, Cohen, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295802/
https://www.ncbi.nlm.nih.gov/pubmed/32541810
http://dx.doi.org/10.1038/s41598-020-66554-0