α-synuclein overexpression in the retina leads to vision impairment and degeneration of dopaminergic amacrine cells

The presence of α-synuclein aggregates in the retina of Parkinson’s disease patients has been associated with vision impairment. In this study we sought to determine the effects of α-synuclein overexpression on the survival and function of dopaminergic amacrine cells (DACs) in the retina. Adult mice...

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Detalles Bibliográficos
Autores principales: Marrocco, Elena, Indrieri, Alessia, Esposito, Federica, Tarallo, Valeria, Carboncino, Anna, Alvino, Filomena Grazia, De Falco, Sandro, Franco, Brunella, De Risi, Maria, De Leonibus, Elvira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295803/
https://www.ncbi.nlm.nih.gov/pubmed/32541823
http://dx.doi.org/10.1038/s41598-020-66497-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295803/
https://www.ncbi.nlm.nih.gov/pubmed/32541823
http://dx.doi.org/10.1038/s41598-020-66497-6

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