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In vitro hypoxia responsiveness of [(18)F] FDG and [(18)F] FAZA retention: influence of shaking versus stagnant conditions, glass versus polystyrene substrata and cell number down-scaling

BACKGROUND: In vitro experiments using radiolabeled molecules is fundamental for Positron emission tomography (PET) or single photon emission computed tomography (SPECT) tracer development and various metabolic assays, but no consensus on appropriate incubation conditions exists. Specifically, the u...

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Detalles Bibliográficos
Autores principales: Busk, Morten, Horsman, Michael R., Overgaard, Jens, Jakobsen, Steen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295868/
https://www.ncbi.nlm.nih.gov/pubmed/32542416
http://dx.doi.org/10.1186/s41181-020-00099-5