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Fc Gamma Receptors and Complement Component 3 Facilitate Anti-fVIII Antibody Formation

Anti-factor VIII (fVIII) alloantibodies, which can develop in patients with hemophilia A, limit the therapeutic options and increase morbidity and mortality of these patients. However, the factors that influence anti-fVIII antibody development remain incompletely understood. Recent studies suggest t...

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Detalles Bibliográficos
Autores principales: Zerra, Patricia E., Arthur, Connie M., Chonat, Satheesh, Maier, Cheryl L., Mener, Amanda, Shin, Sooncheon, Allen, Jerry William L., Baldwin, W. Hunter, Cox, Courtney, Verkerke, Hans, Jajosky, Ryan P., Tormey, Christopher A., Meeks, Shannon L., Stowell, Sean R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295897/
https://www.ncbi.nlm.nih.gov/pubmed/32582142
http://dx.doi.org/10.3389/fimmu.2020.00905