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Adjuvanting Allergen Extracts for Sublingual Immunotherapy: Calcitriol Downregulates CXCL8 Production in Primary Sublingual Epithelial Cells

Application of allergens onto the sublingual epithelium is used to desensitize allergic individuals, a treatment known as sublingual immunotherapy. However, the response of sublingual epithelial cells to house dust mite allergen and potential tolerance-promoting adjuvants such as Toll-like receptor...

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Detalles Bibliográficos
Autores principales: Pelst, Michael P., Höbart, Clara, Wallaeys, Charlotte, De Rooster, Hilde, Gansemans, Yannick, Van Nieuwerburgh, Filip, Devriendt, Bert, Cox, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295906/
https://www.ncbi.nlm.nih.gov/pubmed/32582164
http://dx.doi.org/10.3389/fimmu.2020.01033