Cargando…

Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20

Chemokines are important protein-signaling molecules that regulate various immune responses by activating chemokine receptors which belong to the G protein-coupled receptor (GPCR) superfamily. Despite the substantial progression of our structural understanding of GPCR activation by small molecule an...

Descripción completa

Detalles Bibliográficos
Autores principales: Wasilko, David Jonathan, Johnson, Zachary Lee, Ammirati, Mark, Che, Ye, Griffor, Matthew C., Han, Seungil, Wu, Huixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295996/
https://www.ncbi.nlm.nih.gov/pubmed/32541785
http://dx.doi.org/10.1038/s41467-020-16820-6