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Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20
Chemokines are important protein-signaling molecules that regulate various immune responses by activating chemokine receptors which belong to the G protein-coupled receptor (GPCR) superfamily. Despite the substantial progression of our structural understanding of GPCR activation by small molecule an...
Autores principales: | Wasilko, David Jonathan, Johnson, Zachary Lee, Ammirati, Mark, Che, Ye, Griffor, Matthew C., Han, Seungil, Wu, Huixian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295996/ https://www.ncbi.nlm.nih.gov/pubmed/32541785 http://dx.doi.org/10.1038/s41467-020-16820-6 |
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