Cargando…

Roseotoxin B alleviates cholestatic liver fibrosis through inhibiting PDGF-B/PDGFR-β pathway in hepatic stellate cells

Identifying effective anti-fibrotic therapies is a major clinical need that remains unmet. In the present study, roseotoxin B was shown to possess an improving effect on cholestatic liver fibrosis in bile duct–ligated mice, as proved by histochemical and immunohistochemical staining, hepatic biochem...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xingqi, Gao, Yuzhi, Li, Yu, Huang, Yuqing, Zhu, Yawen, lv, Wei, Wang, Ruzeng, Gou, Lingshan, Cheng, Chao, Feng, Zhaojun, Xie, Jun, Tian, Jun, Yao, Ruiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296008/
https://www.ncbi.nlm.nih.gov/pubmed/32541811
http://dx.doi.org/10.1038/s41419-020-2575-0