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Roseotoxin B alleviates cholestatic liver fibrosis through inhibiting PDGF-B/PDGFR-β pathway in hepatic stellate cells
Identifying effective anti-fibrotic therapies is a major clinical need that remains unmet. In the present study, roseotoxin B was shown to possess an improving effect on cholestatic liver fibrosis in bile duct–ligated mice, as proved by histochemical and immunohistochemical staining, hepatic biochem...
Autores principales: | Wang, Xingqi, Gao, Yuzhi, Li, Yu, Huang, Yuqing, Zhu, Yawen, lv, Wei, Wang, Ruzeng, Gou, Lingshan, Cheng, Chao, Feng, Zhaojun, Xie, Jun, Tian, Jun, Yao, Ruiqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296008/ https://www.ncbi.nlm.nih.gov/pubmed/32541811 http://dx.doi.org/10.1038/s41419-020-2575-0 |
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