Cargando…

A self-sustaining endocytic-based loop promotes breast cancer plasticity leading to aggressiveness and pro-metastatic behavior

The subversion of endocytic routes leads to malignant transformation and has been implicated in human cancers. However, there is scarce evidence for genetic alterations of endocytic proteins as causative in high incidence human cancers. Here, we report that Epsin 3 (EPN3) is an oncogene with prognos...

Descripción completa

Detalles Bibliográficos
Autores principales: Schiano Lomoriello, Irene, Giangreco, Giovanni, Iavarone, Claudia, Tordonato, Chiara, Caldieri, Giusi, Serio, Gaetana, Confalonieri, Stefano, Freddi, Stefano, Bianchi, Fabrizio, Pirroni, Stefania, Bertalot, Giovanni, Viale, Giuseppe, Disalvatore, Davide, Tosoni, Daniela, Malabarba, Maria Grazia, Disanza, Andrea, Scita, Giorgio, Pece, Salvatore, Pilcher, Brian K., Vecchi, Manuela, Sigismund, Sara, Di Fiore, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296024/
https://www.ncbi.nlm.nih.gov/pubmed/32541686
http://dx.doi.org/10.1038/s41467-020-16836-y