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Human ZKSCAN3 and Drosophila M1BP are functionally homologous transcription factors in autophagy regulation

Autophagy is an essential cellular process that maintains homeostasis by recycling damaged organelles and nutrients during development and cellular stress. ZKSCAN3 is the sole identified master transcriptional repressor of autophagy in human cell lines. How ZKSCAN3 achieves autophagy repression at t...

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Detalles Bibliográficos
Autores principales: Barthez, Marine, Poplineau, Mathilde, Elrefaey, Marwa, Caruso, Nathalie, Graba, Yacine, Saurin, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296029/
https://www.ncbi.nlm.nih.gov/pubmed/32541927
http://dx.doi.org/10.1038/s41598-020-66377-z