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Oncogene PRR14 promotes breast cancer through activation of PI3K signal pathway and inhibition of CHEK2 pathway

Nuclear envelope component PRR14 has been detected to be upregulated in varieties of cancers, especially in breast cancer. But its role in breast carcinogenesis is poorly understood. In this study, we show PRR14 contributes to breast carcinogenesis mainly through overexpression, which derives from e...

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Detalles Bibliográficos
Autores principales: Ren, Xiaolei, Long, Meijun, Li, Zhihong, Wu, Boda, Jin, Tao, Tu, Chao, Qi, Lin, Yang, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296039/
https://www.ncbi.nlm.nih.gov/pubmed/32541902
http://dx.doi.org/10.1038/s41419-020-2640-8