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Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion

Demyelination in vascular dementia (VD) is partly attributable to inflammation induced by chronic cerebral hypoperfusion (CCH). Remyelination contributes to the recovery of cognitive impairment by inducing the proliferation and differentiation of oligodendrocyte progenitor cells. It was previously r...

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Detalles Bibliográficos
Autores principales: Li, Meixi, Meng, Nan, Guo, Xin, Niu, Xiaoli, Zhao, Zhongmin, Wang, Wei, Xie, Xiaohua, Lv, Peiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296049/
https://www.ncbi.nlm.nih.gov/pubmed/32581761
http://dx.doi.org/10.3389/fnagi.2020.00137