Reducing Glucokinase Activity to Enhance Insulin Secretion: A Counterintuitive Theory to Preserve Cellular Function and Glucose Homeostasis

Pancreatic beta-cells are the only cells in the body that can synthesize and secrete insulin. Through the process of glucose-stimulated insulin secretion, beta-cells release insulin into circulation, stimulating GLUT4-dependent glucose uptake into peripheral tissue. Insulin is normally secreted in p...

Descripción completa

Detalles Bibliográficos
Autores principales: Whitticar, Nicholas B., Nunemaker, Craig S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296051/
https://www.ncbi.nlm.nih.gov/pubmed/32582035
http://dx.doi.org/10.3389/fendo.2020.00378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296051/
https://www.ncbi.nlm.nih.gov/pubmed/32582035
http://dx.doi.org/10.3389/fendo.2020.00378

Ejemplares similares