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Therapeutic Approaches Targeting Protein Aggregation in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disease that targets motor neurons (MNs) in the brain and spinal cord. It leads to gradual loss of motor signals to muscles leading to atrophy and weakness. Most patients do not survive for more than 3–5 years after disease onse...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296057/ https://www.ncbi.nlm.nih.gov/pubmed/32581709 http://dx.doi.org/10.3389/fnmol.2020.00098 |