Differential Susceptibility and Vulnerability of Brain Cells in C57BL/6 Mouse to Mitochondrial Dysfunction Induced by Short-Term Cuprizone Exposure

Cuprizone (CPZ) is a chemical chelator toxic to mitochondria of cells. While inducing oligodendrocyte (OL) loss and demyelination, CPZ caused no fatal damage to the other brain cells (neurons, astrocytes, and microglia) in previous studies, suggesting differential susceptibility and vulnerability of...

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Detalles Bibliográficos
Autores principales: Luo, Mengyi, Deng, Maomao, Yu, Zijia, Zhang, Yi, Xu, Shuqin, Hu, Shengping, Xu, Haiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroanatomy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296101/
https://www.ncbi.nlm.nih.gov/pubmed/32581731
http://dx.doi.org/10.3389/fnana.2020.00030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296101/
https://www.ncbi.nlm.nih.gov/pubmed/32581731
http://dx.doi.org/10.3389/fnana.2020.00030

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