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The Stronger Downregulation of in vitro and in vivo Innate Antiviral Responses by a Very Virulent Strain of Infectious Bursal Disease Virus (IBDV), Compared to a Classical Strain, Is Mediated, in Part, by the VP4 Protein

IBDV is economically important to the poultry industry. Very virulent (vv) strains cause higher mortality rates than other strains for reasons that remain poorly understood. In order to provide more information on IBDV disease outcome, groups of chickens (n = 18) were inoculated with the vv strain,...

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Detalles Bibliográficos
Autores principales: Dulwich, Katherine L., Asfor, Amin, Gray, Alice, Giotis, Efstathios S., Skinner, Michael A., Broadbent, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296162/
https://www.ncbi.nlm.nih.gov/pubmed/32582573
http://dx.doi.org/10.3389/fcimb.2020.00315