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Dysregulation of Lipid Metabolism in Macrophages Is Responsible for Severe Endotoxin Tolerance in FcgRIIB-Deficient Lupus Mice

FcgRIIB dysfunction is commonly found in patients with lupus, especially in Asia. LPS-tolerance is prominent in FcgRIIB–/– lupus mice. LPS-tolerant macrophages demonstrate cell energy depletion, which might affect lipid metabolism. Therefore, to explore lipid metabolism, LPS-tolerance was induced tw...

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Detalles Bibliográficos
Autores principales:	Jaroonwitchawan, Thiranut, Visitchanakun, Peerapat, Dang, Phi Cong, Ritprajak, Patcharee, Palaga, Tanapat, Leelahavanichkul, Asada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296175/ https://www.ncbi.nlm.nih.gov/pubmed/32582149 http://dx.doi.org/10.3389/fimmu.2020.00959

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