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Interferon Alpha Favors Macrophage Infection by Visceral Leishmania Species Through Upregulation of Sialoadhesin Expression

Type I interferons (IFNs) induced by an endogenous Leishmania RNA virus or exogenous viral infections have been shown to exacerbate infections with New World Cutaneous Leishmania parasites, however, the impact of type I IFNs in visceral Leishmania infections and implicated mechanisms remain to be un...

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Detalles Bibliográficos
Autores principales: Van Bockstal, Lieselotte, Bulté, Dimitri, Van den Kerkhof, Magali, Dirkx, Laura, Mabille, Dorien, Hendrickx, Sarah, Delputte, Peter, Maes, Louis, Caljon, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296180/
https://www.ncbi.nlm.nih.gov/pubmed/32582193
http://dx.doi.org/10.3389/fimmu.2020.01113