Inhibition of acetyl-CoA carboxylase by PP-7a exerts beneficial effects on metabolic dysregulation in a mouse model of diet-induced obesity

Acetyl-coenzyme A carboxylase (ACC) is a critical regulator of fatty acid metabolism and represents a promising therapeutic target for metabolic diseases, including obesity, type 2 diabetes and non-alcoholic fatty liver disease. Recently, a novel ACC inhibitor, PP-7a, was developed by our group by u...

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Detalles Bibliográficos
Autores principales: Liu, Tianya, Gou, Lingshan, Yan, Shirong, Huang, Tonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296295/
https://www.ncbi.nlm.nih.gov/pubmed/32550887
http://dx.doi.org/10.3892/etm.2020.8700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296295/
https://www.ncbi.nlm.nih.gov/pubmed/32550887
http://dx.doi.org/10.3892/etm.2020.8700

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