Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions

Type 2 diabetes (T2D) is a very prevalent, multisystemic, chronic metabolic disorder closely related to atherosclerosis and cardiovascular diseases. It is characterised by mitochondrial dysfunction and the presence of oxidative stress. Metformin is one of the safest and most effective anti-hyperglyc...

Descripción completa

Detalles Bibliográficos
Autores principales: Apostolova, Nadezda, Iannantuoni, Francesca, Gruevska, Aleksandra, Muntane, Jordi, Rocha, Milagros, Victor, Victor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296337/
https://www.ncbi.nlm.nih.gov/pubmed/32535544
http://dx.doi.org/10.1016/j.redox.2020.101517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296337/
https://www.ncbi.nlm.nih.gov/pubmed/32535544
http://dx.doi.org/10.1016/j.redox.2020.101517

Ejemplares similares