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Kainate Receptor Activation Shapes Short-Term Synaptic Plasticity by Controlling Receptor Lateral Mobility at Glutamatergic Synapses

Kainate receptors (KARs) mediate postsynaptic currents with a key impact on neuronal excitability. However, the molecular determinants controlling KAR postsynaptic localization and stabilization are poorly understood. Here, we exploit optogenetic and single-particle tracking approaches to study the...

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Detalles Bibliográficos
Autores principales: Polenghi, Alice, Nieus, Thierry, Guazzi, Stefania, Gorostiza, Pau, Petrini, Enrica Maria, Barberis, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296349/
https://www.ncbi.nlm.nih.gov/pubmed/32521260
http://dx.doi.org/10.1016/j.celrep.2020.107735