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FBXO2 modulates STAT3 signaling to regulate proliferation and tumorigenicity of osteosarcoma cells
BACKGROUND: Osteosarcoma (OS) is the most common primary bone malignancy in children and adolescents, and hyperproliferation of cells is a major problem of OS. FBXO2 belongs to the family of F-box proteins, and is a substrate recognition component of the Skp1-Cul1-F-box protein (SCF) E3 ubiquitin li...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296666/ https://www.ncbi.nlm.nih.gov/pubmed/32549792 http://dx.doi.org/10.1186/s12935-020-01326-4 |