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Repeat-induced point mutation in Neurospora crassa causes the highest known mutation rate and mutational burden of any cellular life
BACKGROUND: Repeat-induced point (RIP) mutation in Neurospora crassa degrades transposable elements by targeting repeats with C→T mutations. Whether RIP affects core genomic sequence in important ways is unknown. RESULTS: By parent-offspring whole genome sequencing, we estimate a mutation rate (3.38...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296669/ https://www.ncbi.nlm.nih.gov/pubmed/32546205 http://dx.doi.org/10.1186/s13059-020-02060-w |