Repeat-induced point mutation in Neurospora crassa causes the highest known mutation rate and mutational burden of any cellular life

BACKGROUND: Repeat-induced point (RIP) mutation in Neurospora crassa degrades transposable elements by targeting repeats with C→T mutations. Whether RIP affects core genomic sequence in important ways is unknown. RESULTS: By parent-offspring whole genome sequencing, we estimate a mutation rate (3.38...

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Detalles Bibliográficos
Autores principales: Wang, Long, Sun, Yingying, Sun, Xiaoguang, Yu, Luyao, Xue, Lan, He, Zhen, Huang, Ju, Tian, Dacheng, Hurst, Laurence D., Yang, Sihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296669/
https://www.ncbi.nlm.nih.gov/pubmed/32546205
http://dx.doi.org/10.1186/s13059-020-02060-w

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