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Metabolic changes associated with adaptive resistance to daptomycin in Streptococcus mitis-oralis

BACKGROUND: Viridans group streptococci of the Streptococcus mitis-oralis subgroup are important endovascular pathogens. They can rapidly develop high-level and durable non-susceptibility to daptomycin both in vitro and in vivo upon exposure to daptomycin. Two consistent genetic adaptations associat...

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Detalles Bibliográficos
Autores principales: Parrett, Allison, Reed, Joseph M., Gardner, Stewart G., Mishra, Nagendra N., Bayer, Arnold S., Powers, Robert, Somerville, Greg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296729/
https://www.ncbi.nlm.nih.gov/pubmed/32539684
http://dx.doi.org/10.1186/s12866-020-01849-w