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DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system
BACKGROUND: CRISPR-Cas systems, which provide adaptive immunity against foreign nucleic acids in prokaryotes, can serve as useful molecular tools for multiple applications in genome engineering. Diverse CRISPR-Cas systems originating from distinct prokaryotes function through a common mechanism invo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296934/ https://www.ncbi.nlm.nih.gov/pubmed/32539804 http://dx.doi.org/10.1186/s12915-020-00799-z |