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DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system

BACKGROUND: CRISPR-Cas systems, which provide adaptive immunity against foreign nucleic acids in prokaryotes, can serve as useful molecular tools for multiple applications in genome engineering. Diverse CRISPR-Cas systems originating from distinct prokaryotes function through a common mechanism invo...

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Detalles Bibliográficos
Autores principales: Tuminauskaite, Donata, Norkunaite, Danguole, Fiodorovaite, Marija, Tumas, Sarunas, Songailiene, Inga, Tamulaitiene, Giedre, Sinkunas, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296934/
https://www.ncbi.nlm.nih.gov/pubmed/32539804
http://dx.doi.org/10.1186/s12915-020-00799-z