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β-Catenin and TCFs/LEF signaling discordantly regulate IL-6 expression in astrocytes
BACKGROUND: The Wnt/β-catenin signaling pathway is a prolific regulator of cell-to-cell communication and gene expression. Canonical Wnt/β-catenin signaling involves partnering of β-catenin with members of the TCF/LEF family of transcription factors (TCF1, TCF3, TCF4, LEF1) to regulate gene expressi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296971/ https://www.ncbi.nlm.nih.gov/pubmed/32546183 http://dx.doi.org/10.1186/s12964-020-00565-2 |