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Association of +138I/D and Lys198Asn Polymorphisms in the Endothelin-1 Gene with Early Onset of Coronary Artery Disease among the Chinese Han Population

BACKGROUND: Human endothelin-1 (ET-1) gene polymorphism is closely associated with coronary artery disease (CAD). This study aimed to investigate the association of 2 single-nucleotide polymorphisms (SNPs), +138 I/D and Lys198Asn) of the ET-1 gene,with early onset of CAD in Han Chinese patients. We...

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Detalles Bibliográficos
Autores principales: Tu, Guosheng, Fang, Zhengxu, Zhao, Yu, Wu, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297021/
https://www.ncbi.nlm.nih.gov/pubmed/32499477
http://dx.doi.org/10.12659/MSM.921542