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Integrative computational epigenomics to build data-driven gene regulation hypotheses

BACKGROUND: Diseases are complex phenotypes often arising as an emergent property of a non-linear network of genetic and epigenetic interactions. To translate this resulting state into a causal relationship with a subset of regulatory features, many experiments deploy an array of laboratory assays f...

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Detalles Bibliográficos
Autores principales: Chen, Tyrone, Tyagi, Sonika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297091/
https://www.ncbi.nlm.nih.gov/pubmed/32543653
http://dx.doi.org/10.1093/gigascience/giaa064