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Integrative computational epigenomics to build data-driven gene regulation hypotheses
BACKGROUND: Diseases are complex phenotypes often arising as an emergent property of a non-linear network of genetic and epigenetic interactions. To translate this resulting state into a causal relationship with a subset of regulatory features, many experiments deploy an array of laboratory assays f...
Autores principales: | Chen, Tyrone, Tyagi, Sonika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297091/ https://www.ncbi.nlm.nih.gov/pubmed/32543653 http://dx.doi.org/10.1093/gigascience/giaa064 |
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