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Role of the central junction in folding topology of the protein-free human U2–U6 snRNA complex
U2 and U6 small nuclear (sn)RNAs are the only snRNAs directly implicated in catalyzing the splicing of pre-mRNA, but assembly and rearrangement steps prior to catalysis require numerous proteins. Previous studies have shown that the protein-free U2–U6 snRNA complex adopts two conformations in equili...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297123/ https://www.ncbi.nlm.nih.gov/pubmed/32220895 http://dx.doi.org/10.1261/rna.073379.119 |