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Modulation of Extracellular ISG15 Signaling by Pathogens and Viral Effector Proteins
ISG15 is a ubiquitin-like modifier that also functions extracellularly, signaling through the LFA-1 integrin to promote interferon (IFN)-γ release from natural killer (NK) and T cells. The signals that lead to the production of extracellular ISG15 and the relationship between its two core functions...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s).
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297157/ https://www.ncbi.nlm.nih.gov/pubmed/32553163 http://dx.doi.org/10.1016/j.celrep.2020.107772 |