Obtaining extremely large and accurate protein multiple sequence alignments from curated hierarchical alignments

For optimal performance, machine learning methods for protein sequence/structural analysis typically require as input a large multiple sequence alignment (MSA), which is often created using query-based iterative programs, such as PSI-BLAST or JackHMMER. However, because these programs align database...

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Detalles Bibliográficos
Autores principales: Neuwald, Andrew F, Lanczycki, Christopher J, Hodges, Theresa K, Marchler-Bauer, Aron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Database Tool
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297217/
https://www.ncbi.nlm.nih.gov/pubmed/32500917
http://dx.doi.org/10.1093/database/baaa042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297217/
https://www.ncbi.nlm.nih.gov/pubmed/32500917
http://dx.doi.org/10.1093/database/baaa042

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