Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha

BACKGROUND: Evidence from both animal and human studies clearly supports the renal beneficial effects of empagliflozin (emp), a sodium glucose co-transporter 2 (SGLT2) inhibitor, but the mechanism in which it exerts its effect is not well understood. In this study, we investigated the capability of...

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Detalles Bibliográficos
Autores principales: Ndibalema, Angelamellisy Revelian, Kabuye, Deo, Wen, Si, Li, Lulu, Li, Xin, Fan, Qiuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297363/
https://www.ncbi.nlm.nih.gov/pubmed/32606855
http://dx.doi.org/10.2147/DMSO.S243170